Zhou Lab

group shot of Zhou lab

Zhou Lab Research Statement

The goal of the Zhou laboratory is to determine the transcriptional regulation of intestinal immune responses. We have characterized the interactions between various transcription factors (e.g., RORγt and Foxp3) involved in specifying development of Th17 cells and the related iTreg lineage as well as how these interactions eventually determine whether the T cell adopts the Th17 or Treg cell fate. We have been focusing on the molecular regulation of innate lymphoid cells (ILCs) by the aryl hydrocarbon receptor (Ahr), a ligand-dependent transcription factor under steady-state physiological conditions, during inflammation or autoimmunity. Most recently, we have extended our studies to host-microbe interactions and metabolic regulation of mucosal immune responses. Our research has implications for understanding how to modulate intestinal immune responses in different disease settings, and it may ultimately lead to the identification of new therapeutic targets for human diseases such as IBD or colon cancer.

The Zhou lab was established in October, 2009 at Northwestern University, Chicago. The lab moved to UF, Gainesville in December, 2015.


Lab Personnel 

Dr. Zhou turning a page, sitting in front of a microscope

Liang Zhou, MD, PhD

Professor

Principal Investigator

 

Kristin Oliff using a pipette

Kristen Oliff

Laboratory Manager

Li using pipette

Shiyang Li

Research Assistant Professor

Zheng Fu uses lab equipment

Zheng Fu

Postdoctoral Fellow

Lifeng Xiong uses a pipette

Lifeng Xiong

Postdoctoral Fellow

Jian Ye uses a pipette

Jian Ye

Postdoctoral Fellow

John Bostick uses an agitator

John Bostick

PhD Student

Joseph Dean using a pipette
Joseph Dean

PhD Student

 


Lab Alumni

 

Zhou lab group shot 2016

Zhou lab group shot 2011
Zhou lab group shot 2012
Zhou lab group shot 2013
Zhou lab group shot 2014

Postdoctoral Fellows:

Ju Qiu (2009 – 2014)
Olga Malykhina (2011)
Lei He (2011 – 2014)
Jianlei Hao (2012 – 2013)
Aki Ueda (2012 – 2014)
Yetao Wang (2013 – 2015)

Graduate Students:

Jennifer Heller (2010 – 2014)
Aki Ueda (2010 – 2012)

Undergraduate Students:

Kyoo Seok Shim (UIC) (2010)
Ari Lederman (2011 – 2012)
Aileen Lee (2011 – 2014)
Jacob Weiderman (UF) (2016 – 2018)

Technicians/Lab Managers:

Priscilla Shamulailatpam (2014 – 2015)
Hui Li (2015 – 2018)

University of Florida

IFAS

As part of both the Institute of Food and Agricultural Sciences and UF Health, Veterinary Medicine is dedicated to advancing animal, human and environmental health through teaching, research, extension and patient care.

IFAS

UNIVERSITY OF FLORIDA

Animal Hospitals

Need animal care? Visit the UF Small Animal and Large Animal Hospitals. From dogs, cats, birds and exotics to horses, cattle, llamas, pigs and many other large farm or food animals, our experienced veterinarian staff is ready to assist.

Animal Airwaves

Syndicated Podcast

Animal Airwaves

Animal Airwaves is a daily radio series that features one-minute segments relating to animal health, ranging from insights into animal behavior to veterinary patient care breakthroughs and trends.

Animal Airwaves