Mycoplasmology and Mucosal Immunity

Mycoplasmal infections present one of the most intriguing paradoxes in infectious diseases. On one hand, the microbe is exquisitely simple with the smallest genome of free-living microorganisms. Conversely, the range of infections and host species are among the most diverse in the microbial world.

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Dr. Dan Brown with biological scientist Dina Michaels in front of the world’s largest mycoplasma specimen collection, housed at UF.

The mycoplasmology and mucosal immunology group is a diverse and interactive group of investigators that include faculty, postdoctoral fellows, graduate students, and laboratory support personnel. The major research areas are to define the pathogenic mechanisms by which mycoplasmas cause both respiratory and urogenital infections in a variety of hosts including humans, rodents, food and fiber animals, and wildlife; to develop models to study virulence factors of mycoplasmas as well as the host response to these pathogens, and to use genomics and proteomics to understand virulence potential.

The group has present and past research funding from diverse sources, including the National Institutes of Health, the National Science Foundation, The Nature Conservancy, USDA, Department of Defense, March of Dimes Birth Defects Foundation, Morris Animal Foundation, and Bureau of Land Management.