Lifeng Xiong

Postdoctoral Fellow

Lifeng Xiong using a multichannel pipette.

Department of Infectious Diseases & Immunology

PO Box 110880

2015 SW 16th Ave

Gainesville, FL 32611-0880


FAX 352-392-9704



  • PhD, University of Hong Kong, 2015


Research Interests

While studying as a PhD student, I investigated the interactions of pathogenic bacteria, host cells, and environmental stressors. I specialized in clarifying the mechanisms of the arginine deiminase pathway for bacterial adaptation to acidic conditions, anaerobic stress, and other host defenses encountered during infection and in environmental niches. The Zhou lab has provided me with an excellent environment for immunological study. I am most interested in the mucosal relationship of the immune system, the body’s exposure to pathogens, and the microbiome, and I plan to use my research experience to pursue study in every branch of immunology.


Recent Publications

  • Xiong L, Wang S, Dean JW, Oliff KN, Jobin C, Curtiss R 3rd, Zhou L. Group 3 innate lymphoid cell pyroptosis represents a host defense mechanism against Salmonella infection. Nat Microbiol. 2022; 7(7):1087-1099.
  • Xiong L, Dean JW, Fu Z, Oliff KN, Bostick JW, Ye J, Chen ZE, Mühlbauer M, Zhou L. Ahr-Foxp3-RORγt axis controls gut homing of CD4+ T cells by regulating GPR15. Sci Immunol. 2020; 5(48):eaaz7277.
  • Fu Z, Dean JW, Xiong L, Dougherty MW, Oliff KN, Chen ZE, Jobin C, Garret TJ, Zhou L. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021; 12(1):4462.

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